Journal
MOLECULAR PHYLOGENETICS AND EVOLUTION
Volume 67, Issue 2, Pages 541-545Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.ympev.2013.02.013
Keywords
De novo origin; New gene; Evolution
Funding
- National Natural Science Foundation of China [31271339]
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De novo origination has recently been appreciated to be an important mechanism contributing to the origin of genes. Evidence indicates that de novo originated genes can evolve important and even essential functions rapidly. We present an adaptation following neutrality process to explain the evolution of essential function of new genes. How new de novo originated genes become involved in pathways and interact with other old genes, and the exact functions of these new genes, however, remains largely undocumented. Examinations of the function of de novo origin and the function of noncoding RNA genes should become more frequent and appreciated in the future studies. (C) 2013 Elsevier Inc. All rights reserved.
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