Journal
MOLECULAR NUTRITION & FOOD RESEARCH
Volume 57, Issue 8, Pages 1347-1358Publisher
WILEY
DOI: 10.1002/mnfr.201200828
Keywords
Fluxes; Leukotrienes; Metabolism; Peroxidation; Prostanoids
Categories
Funding
- INSA-Lyon
- Inserm
- IBiSA Functional Lipidomics platform
- LISA Carnot institute
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Polyunsaturated fatty acids in mammals may be oxygenated into a myriad of bioactive products through di- and monooxygenases, products that are rapidly degraded to control their action. To evaluate the phenotypes of biological systems regarding this wide family of compounds, a lipidomics approach in function of time and compartments would be relevant. The current review takes into consideration most of the diverse oxygenated metabolites of essential fatty acids at large and their immediate degradation products. Their biological function and life span are considered. Overall, this is a fluxolipidomics approach that is emerging.
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