Journal
SCIENCE SIGNALING
Volume 8, Issue 367, Pages -Publisher
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/scisignal.aaa3312
Keywords
-
Categories
Funding
- Telethon Foundation Italy [GGP12126]
- AIRC (Associazione Italiana per la Ricerca sul Cancro) [IG15530]
- Italian Ministry for Research [PRIN-20108MXN2J]
Ask authors/readers for more resources
Specialized regions of the plasma membrane dedicated to diverse cellular processes, such as vesicle exocytosis, extracellular matrix remodeling, and cell migration, share a few cytosolic scaffold proteins that associate to form large plasma membrane-associated platforms (PMAPs). PMAPs organize signaling events and trafficking of membranes and molecules at specific membrane domains. On the basis of the intrinsic disorder of the proteins constituting the core of these PMAPs and of the dynamics of these structures at the periphery of motile cells, we propose a working model for the assembly and turnover of these platforms.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available