4.5 Article

The efficacy of autologous platelet-rich plasma combined with erbium fractional laser therapy for facial acne scars or acne

Journal

MOLECULAR MEDICINE REPORTS
Volume 8, Issue 1, Pages 233-237

Publisher

SPANDIDOS PUBL LTD
DOI: 10.3892/mmr.2013.1455

Keywords

fractional laser; platelet-rich plasma; acne; scar

Funding

  1. National Basic Science and Development Program of China (973 Program) [2012CB518105]
  2. Major National Science and Technology Programs [2011ZXJ09104-07C]
  3. National Nature and Science Foundation of China [81171812]
  4. Guangdong Provincial Science and Technology Projects [2009B080701092, 2011B061300073]
  5. Guangzhou City Science and Technology Project [10C36091671, 2012J4100044]

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The aim of this study was to evaluate the efficacy of autologous platelet-rich plasma (PRP) combined with erbium fractional laser therapy for facial acne or acne scars. PRP combined with erbium fractional laser therapy was used for the treatment of 22 patients, including 16 patients who suffered from facial acne scars and 6 patients who suffered from acne scars concomitant with acne. Whole blood (40 ml) was collected from each patient, and following differential centrifugation, PRP was harvested. After using an erbium fractional laser, we applied PRP to the entire face of every patient. Digital photos were taken before and after the treatment for evaluation by dermatologists and the patients rated the efficacy on a 5-point scale. The erythema was moderate or mild, while its total duration was <3 days; after receiving the treatment three times, 90.9% of the patients showed an improvement of >50%, and 91% of the patients were satisfied; no acne inflammation was observed after treatment. PRP combined with erbium fractional laser therapy is an effective and safe approach for treating acne scars or acne, with minimal side-effects, and it simultaneously enhanced the recovery of laser-damaged skin.

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