Related references
Note: Only part of the references are listed.p63 sustains self-renewal of mammary cancer stem cells through regulation of Sonic Hedgehog signaling
Elisa Maria Memmi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
ΔNP63α Transcriptionally Activates Chemokine Receptor 4 (CXCR4) Expression to Regulate Breast Cancer Stem Cell Activity and Chemotaxis
Andrew J. DeCastro et al.
MOLECULAR CANCER THERAPEUTICS (2015)
p63 is a prosurvival factor in the adult mammary gland during post-lactational involution, affecting PI-MECs and ErbB2 tumorigenesis
A. R. Yallowitz et al.
CELL DEATH AND DIFFERENTIATION (2014)
ΔNp63 promotes stem cell activity in mammary gland development and basal-like breast cancer by enhancing Fzd7 expression and Wnt signalling
Rumela Chalcrabarti et al.
NATURE CELL BIOLOGY (2014)
ΔNp63α-Mediated Activation of Bone Morphogenetic Protein Signaling Governs Stem Cell Activity and Plasticity in Normal and Malignant Mammary Epithelial Cells
Amanda L. Balboni et al.
CANCER RESEARCH (2013)
Wnt signaling in stem and cancer stem cells
Jane D. Holland et al.
CURRENT OPINION IN CELL BIOLOGY (2013)
Notch signaling represses p63 expression in the developing surface ectoderm
Ana Mafalda Baptista Tadeu et al.
DEVELOPMENT (2013)
Cbx4 regulates the proliferation of thymic epithelial cells and thymus function
Bo Liu et al.
DEVELOPMENT (2013)
Role of p63 and the Notch pathway in cochlea development and sensorineural deafness
Alessandro Terrinoni et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
p63-expressing cells are the stem cells of developing prostate, bladder, and colorectal epithelia
Jean-Christophe Pignon et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
p63 steps into the limelight: crucial roles in the suppression of tumorigenesis and metastasis
Xiaohua Su et al.
NATURE REVIEWS CANCER (2013)
ΔNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation
Rose-Anne Romano et al.
DEVELOPMENT (2012)
Increased p63 Phosphorylation Marks Early Transition of Epidermal Stem Cells to Progenitors
Daisuke Suzuki et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2012)
Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer
Paola Tucci et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Notch signaling mediates p63-induced quiescence: A new facet of p63/Notch crosstalk
Nicole Forster et al.
CELL CYCLE (2011)
ΔNp63α promotes cellular quiescence via induction and activation of Notch3
Sierra Kent et al.
CELL CYCLE (2011)
p63 is a suppressor of tumorigenesis and metastasis interacting with mutant p53
G. Melino
CELL DEATH AND DIFFERENTIATION (2011)
p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis
Michael Y. Fessing et al.
JOURNAL OF CELL BIOLOGY (2011)
p63, a Story of Mice and Men
Hans Vanbokhoven et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2011)
The p53 family: guardians of maternal reproduction
Arnold J. Levine et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2011)
p63 Regulates Olfactory Stem Cell Self-Renewal and Differentiation
Russell B. Fletcher et al.
NEURON (2011)
p63 in Epithelial Survival, Germ Cell Surveillance, and Neoplasia
Christopher P. Crum et al.
ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2010)
Overexpression of ΔNp63α induces a stem cell phenotype in MCF7 breast carcinoma cell line through the Notch pathway
Zhijian Du et al.
CANCER SCIENCE (2010)
Biological and Molecular Heterogeneity of Breast Cancers Correlates with Their Cancer Stem Cell Content
Salvatore Pece et al.
CELL (2010)
Antagonistic roles of Notch and p63 in controlling mammary epithelial cell fates
Oe Yalcin-Ozuysal et al.
CELL DEATH AND DIFFERENTIATION (2010)
Genome-Wide Profiling of p63 DNA-Binding Sites Identifies an Element that Regulates Gene Expression during Limb Development in the 7q21 SHFM1 Locus
Evelyn N. Kouwenhoven et al.
PLOS GENETICS (2010)
Lin-Sca-1+CD49fhigh Stem/Progenitors Are Tumor-Initiating Cells in the Pten-Null Prostate Cancer Model
David J. Mulholland et al.
CANCER RESEARCH (2009)
The Tumor Suppressor p53 Regulates Polarity of Self-Renewing Divisions in Mammary Stem Cells
Angelo Cicalese et al.
CELL (2009)
Mutant p53 Drives Invasion by Promoting Integrin Recycling
Patricia A. J. Muller et al.
CELL (2009)
A Mutant-p53/Smad Complex Opposes p63 to Empower TGFβ-Induced Metastasis
Maddalena Adorno et al.
CELL (2009)
TAp63 induces senescence and suppresses tumorigenesis in vivo
Xuecui Guo et al.
NATURE CELL BIOLOGY (2009)
Notch Signaling Regulates Mammary Stem Cell Function and Luminal Cell-Fate Commitment
Toula Bouras et al.
CELL STEM CELL (2008)
Reciprocal intraepithelial interactions between TP63 and hedgehog signaling regulate quiescence and activation of progenitor elaboration by mammary stem cells
Na Li et al.
STEM CELLS (2008)
Characterization of adult prostatic progenitor/stem cells exhibiting self-renewal and multilineage differentiation
Wendy W. Barclay et al.
STEM CELLS (2008)
ΔNp63 isoforms regulate CD44 and keratins 4, 6, 14 and 19 in squamous cell carcinoma of head and neck
L. Boldrup et al.
JOURNAL OF PATHOLOGY (2007)
Self-renewal and multilineage differentiation in vitro from murine prostate stem cells
Li Xin et al.
STEM CELLS (2007)
Structural evolution of C-terminal domains in the p53 family
Horng Der Ou et al.
EMBO JOURNAL (2007)
ΔNp63 regulates thymic development through enhanced expression of FgfR2 and Jag2
Eleonora Candi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Loss of a quiescent niche but not follicle stem cells in the absence of bone morphogenetic protein signaling
Krzysztof Kobielak et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
p63 is essential for the proliferative potential of stem cells in stratified epithelia
Makoto Senoo et al.
CELL (2007)
The p63/p73 network mediates chemosensitivity to cisplatin in a biologically defined subset of primary breast cancers
Chee-Onn Leong et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
TAp63 and ΔNp63 in cancer and epidermal development
Eleonora Candi et al.
CELL CYCLE (2007)
Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma
M. E. Prince et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Identification of new p63 targets in human keratinocytes
Barbara Testoni et al.
CELL CYCLE (2006)
p63 protects the female germ line during meiotic arrest
Eun-Kyung Suh et al.
NATURE (2006)
New p63 targets in keratinocytes identified by a genome-wide approach
M. Alessandra Vigano et al.
EMBO JOURNAL (2006)
Asymmetric and symmetric stem-cell divisions in development and cancer
Sean J. Morrison et al.
NATURE (2006)
Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells
Suling Liu et al.
CANCER RESEARCH (2006)
Differential roles of p63 isoforms in epidermal development: selective genetic complementation in p63 null mice
E. Candi et al.
CELL DEATH AND DIFFERENTIATION (2006)
p63 regulates an adhesion programme and cell survival in epithelial cells
Danielle K. Carroll et al.
NATURE CELL BIOLOGY (2006)
p63 heterozygous mutant mice are not prone to spontaneous or chemically induced tumors
William M. Keyes et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation
BC Nguyen et al.
GENES & DEVELOPMENT (2006)
The unique NH2-terminally deleted (ΔN) residues, the PXXP motif, and the PPXY motif are required for the transcriptional activity of the ΔN variant of p63
ES Helton et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Generation of a functional mammary gland from a single stem cell
M Shackleton et al.
NATURE (2006)
P53 suppresses the self-renewal of adult neural stem cells
K Meletis et al.
DEVELOPMENT (2006)
p53/p63/p73 isoforms: an orchestra of isoforms to harmonise cell differentiation and response to stress
F. Murray-Zmijewski et al.
CELL DEATH AND DIFFERENTIATION (2006)
Asymmetric cell divisions promote stratification and differentiation of mammalian skin
T Lechler et al.
NATURE (2005)
p63 regulates commitment to the prostate cell lineage
S Signoretti et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Differential recognition of response elements determines target gene specificity for p53 and p63
M Osada et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Sca-1 expression identifies stem cells in the proximal region of prostatic ducts with high capacity to reconstitute prostatic tissue
PE Burger et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Tumor predisposition in mice mutant for p63 and p73:: Evidence for broader tumor suppressor functions for the p53 family
ER Flores et al.
CANCER CELL (2005)
Perp is a p63-regulated gene essential for epithelial integrity
RA Ihrie et al.
CELL (2005)
p63 is the molecular switch for initiation of an epithelial stratification program
MI Koster et al.
GENES & DEVELOPMENT (2004)
p51/p63 controls subunit α3 of the major epidermis integrin anchoring the stem cells to the niche
S Kurata et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells
G Dontu et al.
BREAST CANCER RESEARCH (2004)
TP53 family members and human cancers
J Bénard et al.
HUMAN MUTATION (2003)
Functional regulation of p73 and p63: development and cancer
G Melino et al.
TRENDS IN BIOCHEMICAL SCIENCES (2003)
Differential expression of p63 isoforms in normal tissues and neoplastic cells
K Nylander et al.
JOURNAL OF PATHOLOGY (2002)
p63 and p73 are required for p53-dependent apoptosis in response to DNA damage
ER Flores et al.
NATURE (2002)
p63, a p53 homologue, is a selective nuclear marker of myoepithelial cells of the human breast
M Barbareschi et al.
AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2001)
p63 is a prostate basal cell marker and is required for prostate development
S Signoretti et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)