Related references
Note: Only part of the references are listed.Aberrant MEK5/ERK5 signalling contributes to human colon cancer progression via NF-κB activation
A. E. S. Simoes et al.
CELL DEATH & DISEASE (2015)
FSL-1 Induces MMP-9 Production through TLR-2 and NF-κB/AP-1 Signaling Pathways in Monocytic THP-1 Cells
Rasheed Ahmad et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2014)
Proresolving Lipid Mediators and Mechanisms in the Resolution of Acute Inflammation
Christopher D. Buckley et al.
IMMUNITY (2014)
Identification of Activators of ERK5 Transcriptional Activity by High-Throughput Screening and the Role of Endothelial ERK5 in Vasoprotective Effects Induced by Statins and Antimalarial Agents
Nhat-Tu Le et al.
JOURNAL OF IMMUNOLOGY (2014)
Phosphoproteomic evaluation of pharmacological inhibition of leucine-rich repeat kinase 2 reveals significant off-target effects of LRRK-2-IN-1
Gregory C. Luerman et al.
JOURNAL OF NEUROCHEMISTRY (2014)
Biological basis and pathological relevance of microvascular thrombosis
Susanne Pfeiler et al.
THROMBOSIS RESEARCH (2014)
Pathophysiology of microcirculatory dysfunction and the pathogenesis of septic shock
Daniel De Backer et al.
VIRULENCE (2014)
Extracellular signal-regulated kinase-5: Novel mediator of insulin and tumor necrosis factor α-stimulated vascular cell adhesion molecule-1 expression in vascular cells
Daniel Z. Mackesy et al.
JOURNAL OF DIABETES (2014)
ERK5 Inhibition Ameliorates Pulmonary Fibrosis via Regulating Smad3 Acetylation
Suji Kim et al.
AMERICAN JOURNAL OF PATHOLOGY (2013)
Statins protect human endothelial cells from TNF-induced inflammation via ERK5 activation
Ke Wu et al.
BIOCHEMICAL PHARMACOLOGY (2013)
De-SUMOylation Enzyme of Sentrin/SUMO-Specific Protease 2 Regulates Disturbed Flow-Induced SUMOylation of ERK5 and p53 that Leads to Endothelial Dysfunction and Atherosclerosis
Kyung-Sun Heo et al.
CIRCULATION RESEARCH (2013)
Potent Antimyeloma Activity of a Novel ERK5/CDK Inhibitor
Stela Alvarez-Fernandez et al.
CLINICAL CANCER RESEARCH (2013)
Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2 activities of benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-ones
Xianming Deng et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2013)
Extracellular Signal-regulated Kinase 5 (ERK5) Mediates Prolactin-stimulated Adult Neurogenesis in the Subventricular Zone and Olfactory Bulb
Wenbin Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Structural Mechanism for the Specific Assembly and Activation of the Extracellular Signal Regulated Kinase 5 (ERK5) Module
Gabor Glatz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
X-ray Crystal Structure of ERK5 (MAPK7) in Complex with a Specific Inhibitor
Jonathan M. Elkins et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
CX3CL1/CX3CR1 regulates nerve injury-induced pain hypersensitivity through the ERK5 signaling pathway
Jian-Liang Sun et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2013)
Targeted Deletion of the ERK5 MAP Kinase Impairs Neuronal Differentiation, Migration, and Survival during Adult Neurogenesis in the Olfactory Bulb
Tan Li et al.
PLOS ONE (2013)
Correction: Inducible and Targeted Deletion of the ERK5 MAP Kinase in Adult Neurogenic Regions Impairs Adult Neurogenesis in the Olfactory Bulb and Several Forms of Olfactory Behavior
Yung-Wei Pan et al.
PLoS One (2013)
Role of Fibrinolysis in Sepsis
Satoshi Gando
SEMINARS IN THROMBOSIS AND HEMOSTASIS (2013)
Quantitative In vitro Assay to Measure Neutrophil Adhesion to Activated Primary Human Microvascular Endothelial Cells under Static Conditions
Kevin Wilhelmsen et al.
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2013)
Mitogen-activated protein kinases in innate immunity
J. Simon C. Arthur et al.
NATURE REVIEWS IMMUNOLOGY (2013)
Alveolar Macrophages and Toll-like Receptor 4 Mediate Ventilated Lung Ischemia Reperfusion Injury in Mice
Arun Prakash et al.
ANESTHESIOLOGY (2012)
PAI-1, progress in understanding the clinical problem and its aetiology
Takayuki Iwaki et al.
BRITISH JOURNAL OF HAEMATOLOGY (2012)
ERK5: Structure, regulation and function
Gopika N. Nithianandarajah-Jones et al.
CELLULAR SIGNALLING (2012)
Role of Complement in Multiorgan Failure
Daniel Rittirsch et al.
CLINICAL & DEVELOPMENTAL IMMUNOLOGY (2012)
Activation of endothelial TLR2 by bacterial lipoprotein upregulates proteins specific for the neutrophil response
Kevin Wilhelmsen et al.
INNATE IMMUNITY (2012)
ERK5 Protein Promotes, whereas MEK1 Protein Differentially Regulates, the Toll-like Receptor 2 Protein-dependent Activation of Human Endothelial Cells and Monocytes
Kevin Wilhelmsen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Inducible and Conditional Deletion of Extracellular Signal-regulated Kinase 5 Disrupts Adult Hippocampal Neurogenesis
Yung-Wei Pan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Laminar Flow Activation of ERK5 Protein in Vascular Endothelium Leads to Atheroprotective Effect via NF-E2-related Factor 2 (Nrf2) Activation
Miso Kim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Targeted Deletion of ERK5 MAP Kinase in the Developing Nervous System Impairs Development of GABAergic Interneurons in the Main Olfactory Bulb and Behavioral Discrimination between Structurally Similar Odorants
Junhui Zou et al.
JOURNAL OF NEUROSCIENCE (2012)
The Role of Src Kinase inMacrophage-Mediated Inflammatory Responses
Se Eun Byeon et al.
MEDIATORS OF INFLAMMATION (2012)
Sepsis, thrombosis and organ dysfunction
Nicola Semeraro et al.
THROMBOSIS RESEARCH (2012)
Patterns and early evolution of organ failure in the intensive care unit and their relation to outcome
Yasser Sakr et al.
CRITICAL CARE (2012)
ERK5 signalling in prostate cancer promotes an invasive phenotype
A. K. Ramsay et al.
BRITISH JOURNAL OF CANCER (2011)
Targeting the BMK1 MAP Kinase Pathway in Cancer Therapy
Qingkai Yang et al.
CLINICAL CANCER RESEARCH (2011)
Bacterial Lipoprotein TLR2 Agonists Broadly Modulate Endothelial Function and Coagulation Pathways In Vitro and In Vivo
Hae-Sook Shin et al.
JOURNAL OF IMMUNOLOGY (2011)
Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases
Marie Cargnello et al.
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2011)
MEK5 is Activated by Shear Stress, Activates ERK5 and Induces KLF4 to Modulate TNF Responses in Human Dermal Microvascular Endothelial Cells
Paul R. Clark et al.
MICROCIRCULATION (2011)
Microvascular Thrombosis: A Serious and Deadly Pathologic Process in Multiple Diseases
Hau C. Kwaan
SEMINARS IN THROMBOSIS AND HEMOSTASIS (2011)
ERK5 pathway regulates the phosphorylation of tumour suppressor hDlg during mitosis
Francisco A. Inesta-Vaquera et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
Structure-activity relationships of benzimidazole-based selective inhibitors of the mitogen activated kinase-5 signaling pathway
Patrick T. Flaherty et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2010)
Identification of benzimidazole-based inhibitors of the mitogen activated kinase-5 signaling pathway
Patrick T. Flaherty et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)
Pharmacological Inhibition of BMK1 Suppresses Tumor Growth through Promyelocytic Leukemia Protein
Qingkai Yang et al.
CANCER CELL (2010)
Erk5 Activation Elicits a Vasoprotective Endothelial Phenotype via Induction of Kruppel-like Factor 4 (KLF4)
Nils Ohnesorge et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
TLR2-and Nucleotide-Binding Oligomerization Domain 2-Dependent Kruppel-Like Factor 2 Expression Downregulates NF-κB-Related Gene Expression
Janine Zahlten et al.
JOURNAL OF IMMUNOLOGY (2010)
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
Taro Kawai et al.
NATURE IMMUNOLOGY (2010)
Intravascular Danger Signals Guide Neutrophils to Sites of Sterile Inflammation
Braedon McDonald et al.
SCIENCE (2010)
Regulation of Adaptive Immunity by the Innate Immune System
Akiko Iwasaki et al.
SCIENCE (2010)
Sterile inflammation: sensing and reacting to damage
Grace Y. Chen et al.
NATURE REVIEWS IMMUNOLOGY (2010)
Regulation and Function of NF-kappa B Transcription Factors in the Immune System
Sivakumar Vallabhapurapu et al.
ANNUAL REVIEW OF IMMUNOLOGY (2009)
ERK5 and the regulation of endothelial cell function
Owain Llyr Roberts et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2009)
Targeting protein kinases for the development of anti-inflammatory drugs
Philip Cohen
CURRENT OPINION IN CELL BIOLOGY (2009)
Expression of Erk5 in Early Stage Breast Cancer and Association with Disease Free Survival Identifies this Kinase as a Potential Therapeutic Target
Juan Carlos Montero et al.
PLOS ONE (2009)
Intravascular immunity: the host-pathogen encounter in blood vessels
Michael J. Hickey et al.
NATURE REVIEWS IMMUNOLOGY (2009)
Mechanisms and consequences of neutrophil interaction with the endothelium
Alexander Zarbock et al.
AMERICAN JOURNAL OF PATHOLOGY (2008)
HGF mediates cell proliferation of human mesothelioma cells through a PI3K/MEK5/Fra-1 pathway
Maria E. Ramos-Nino et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2008)
Fluid shear stress inhibits TNF-mediated JNK activation via MEKS-BMK1 in endothelial cells
Lingli Li et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Identification of pharmacological inhibitors of the MEK5/ERK5 pathway
Revati J. Tatake et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
ERK5 regulation in naive T-cell activation and survival
Olga Ananieva et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2008)
KLF2-dependent, shear stress-induced expression of CD59 - A novel cytoprotective mechanism against complement-mediated injury in the vasculature
Anne R. Kinderlerer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Regulation of TLR2 expression by prostaglandins in brain glia
Hee Jung Yoon et al.
JOURNAL OF IMMUNOLOGY (2008)
Origin and physiological roles of inflammation
Ruslan Medzhitov
NATURE (2008)
Activation of MAP kinase signaling through ERK5 but not ERK1 expression is associated with lymph node metastases in oral squamous cell carcinoma (OSCC)
Carsten Sticht et al.
NEOPLASIA (2008)
Aberrant expression of extracellular signal-regulated kinase 5 in human prostate cancer
S. R. C. McCracken et al.
ONCOGENE (2008)
Inflammation, endothelium, and coagulation in sepsis
Marcel Schouten et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2008)
Harmful molecular mechanisms in sepsis
Daniel Rittirsch et al.
NATURE REVIEWS IMMUNOLOGY (2008)
Activator protein 1 (Fos/Jun) functions in inflammatory bone and skin disease
Rainer Zenz et al.
ARTHRITIS RESEARCH & THERAPY (2008)
Activation of a C-terminal transcriptional activation domain of ERK5 by autophosphorylation
Hiroko Morimoto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Systemic inflammation after trauma
Andreas Lenz et al.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED (2007)
Regulation of the G2-M cell cycle progression by the ERK5-NFκB signaling pathway
Kelly Cude et al.
JOURNAL OF CELL BIOLOGY (2007)
Comprehensive analysis of homeobox genes in Hodgkin lymphoma cell lines identifies dysregulated expression of HOXB9 mediated via ERK5 signaling and BMI1
Stefan Nagel et al.
BLOOD (2007)
Getting to the site of inflammation: the leukocyte adhesion cascade updated
Klaus Ley et al.
NATURE REVIEWS IMMUNOLOGY (2007)
ERK5 activates NF-κB in leukemic T cells and is essential for their growth in vivo
Johan Garaude et al.
JOURNAL OF IMMUNOLOGY (2006)
ERK5 activation inhibits inflammatory responses via peroxisome proliferator-activated receptor δ (PPARδ) stimulation
Chang-Hoon Woo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Spatiotemporal regulation of c-Fos by ERK5 and the E3 ubiquitin ligase UBR1, and its biological role
Takanori Sasaki et al.
MOLECULAR CELL (2006)
The MAP kinase ERK5 binds to and phosphorylates p90 RSK
Aarati Ranganathan et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2006)
Integration of flow-dependent endothelial phenotypes by Kruppel-like factor 2
KM Parmar et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Causes of death and determinants of outcome in critically ill patients
Viktoria D. Mayr et al.
CRITICAL CARE (2006)
Transcriptional regulation of tissue-specific genes by the ERK5 mitogen-activated protein kinase
SJ Sohn et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Big mitogen-activated protein kinase 1/extracellular signal-regulated kinase 5 signaling pathway is essential for tumor-associated angiogenesis
M Hayashi et al.
CANCER RESEARCH (2005)
Inhibition of vascular permeability factor/vascular endothelial growth factor-mediated angiogenesis by the Kruppel-like factor KLF2
R Bhattacharya et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Kruppel-like factor 2 (KLF2) regulates endothelial thrombotic function
ZY Lin et al.
CIRCULATION RESEARCH (2005)
The unique C-terminal tail of the mitogen-activated protein kinase ERK5 regulates its activation and nuclear shuttling
M Buschbeck et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Targeted deletion of BMK1/ERK5 in adult mice perturbs vascular integrity and leads to endothelial failure
M Hayashi et al.
JOURNAL OF CLINICAL INVESTIGATION (2004)
14-3-3β binds to big mitogen-activated protein kinase 1 (BMK1/ERK5) and regulates BMK1 function
QL Zheng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
WNK1 activates ERK5 by an MEKK2/3-dependent mechanism
BE Xu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The hinge-helix 1 region of peroxisome proliferator-activated receptor γ1 (PPARγ1) mediates interaction with extracellular signal-regulated kinase 5 and PPARγ1 transcriptional activation:: Involvement in flow-induced PPARγ activation in endothelial cells
M Akaike et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Characterization of the MEK5-ERK5 module in human neutrophils and its relationship to ERK1/ERK2 in the chemotactic response
CS Hii et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
KLF2 is a novel transcriptional regulator of endothelial proinflammatory activation
S SenBanerjee et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
Multiple organ failure in trauma patients
RM Durham et al.
JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE (2003)
Sepsis and disseminated intravascular coagulation
M Levi et al.
JOURNAL OF THROMBOSIS AND THROMBOLYSIS (2003)
An analysis of the phosphorylation and activation of extracellular-signal-regulated protein kinase 5 (ERK5) by mitogen-activated protein kinase kinase 5 (MKK5) in vitro
N Mody et al.
BIOCHEMICAL JOURNAL (2003)
Regulation of epidermal growth factor-induced connexin 43 gap junction communication by big mitogen-activated protein kinase 1/ERK5 but not ERK1/2 kinase activation
SJ Cameron et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The epidemiology of sepsis in the United States from 1979 through 2000
GS Martin et al.
NEW ENGLAND JOURNAL OF MEDICINE (2003)
MEK kinase 2 and the adaptor protein Lad regulate extracellular signal-regulated kinase 5 activation by epidermal growth factor via Src
WY Sun et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
MEK5 overexpression is associated with metastatic prostate cancer, and stimulates proliferation, MMP-9 expression and invasion
PB Mehta et al.
ONCOGENE (2003)
Regulation of c-Fos and Fra-1 by the MEK5-ERK5 pathway
K Terasawa et al.
GENES TO CELLS (2003)
ERK5 MAPK regulates embryonic angiogenesis and acts as a hypoxia-sensitive repressor of vascular endothelial growth factor expression
SJ Sohn et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Identification of mitogen-activated protein kinase kinase as a chemoresistant pathway in MCF-7 cells by using gene expression microarray
CB Weldon et al.
SURGERY (2002)
Erk5 null mice display multiple extraembryonic vascular and embryonic cardiovascular defects
CP Regan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Erk5 participates in neuregulin signal transduction and is constitutively active in breast cancer cells overexpressing ErbB2
A Esparis-Ogando et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
AP-1 in cell proliferation and survival
E Shaulian et al.
ONCOGENE (2001)
BMK1 mediates growth factor-induced cell proliferation through direct cellular activation of serum and glucocorticoid-inducible kinase
M Hayashi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
ERK5 and ERK2 cooperate to regulate NF-κB and cell transformation
G Pearson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
MEKK2 associates with the adapter protein Lad/RIBP and regulates the MEK5-BMK1/ERK5 pathway
WY Sun et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Big mitogen-activated kinase regulates multiple members of the MEF2 protein family
Y Kato et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Regulation of TNF expression by multiple mitogen-activated protein kinase pathways
W Zhu et al.
JOURNAL OF IMMUNOLOGY (2000)
A simple method for human peripheral blood monocyte isolation
MC de Almeida et al.
MEMORIAS DO INSTITUTO OSWALDO CRUZ (2000)
Multiple mitogen-activated protein kinase signaling pathways connect the Cot oncoprotein to the c-jun promoter and to cellular transformation
M Chiariello et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Share Paper
