Journal
MOLECULAR DIVERSITY
Volume 18, Issue 4, Pages 887-893Publisher
SPRINGER
DOI: 10.1007/s11030-014-9531-9
Keywords
Multicomponent; Petasis-borono Mannich reaction; Fused morpholines; Insecticidal activity; MCR
Categories
Funding
- National Basic Research Program of China (973 Program) [2010CB126101]
- National Natural Science Foundation of China [20972052]
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A simple and efficient synthesis of fused morpholine pyrrolidine/piperdine core structures was accomplished via a Petasis-borono Mannich reaction of cyclic amino alcohols, glyoxal and arylboronic acids with moderate to good yields. The bioassay data showed that the synthesized compounds displayed selective insecticidal activities against armyworm and root-knot nematode.
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