Journal
MOLECULAR DIVERSITY
Volume 18, Issue 4, Pages 821-828Publisher
SPRINGER
DOI: 10.1007/s11030-014-9541-7
Keywords
Highly functionalized cyclohexenone; 2-Oxo-N,4,6-triarylcyclohex-3-enecarboxamide; Ionic liquid; One-pot; 2-Hydroxyethylammonium acetate
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Funding
- Research Council of the University of Sistan and Baluchestan
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A series of 2-oxo-N,4,6-triarylcyclohex-3-enecarboxamides were synthesized by condensing acetophenone and aromatic aldehydes with acetoacetanilide in ethanol in the presence of 2-hydroxyethylammonium acetate (2-HEAA) as a basic ionic liquid at ambient conditions. This process is simple, efficient and environmentally benign and proceeds in high yield, short reaction times and there is no need for column chromatography purification.
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