4.5 Article

The flow synthesis of heterocycles for natural product and medicinal chemistry applications

Journal

MOLECULAR DIVERSITY
Volume 15, Issue 3, Pages 613-630

Publisher

SPRINGER
DOI: 10.1007/s11030-010-9282-1

Keywords

Flow synthesis; Micro-reactor; Meso-reactor; Solid-supported reagents; Heterocycles; Automated synthesis

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This article represents an overview of recent research from the Innovative Technology Centre in the field of flow chemistry which was presented at the FROST2 meeting in Budapest in October 2009. After a short introduction of this rapidly expanding field, we discuss some of our results with a main focus on the synthesis of heterocyclic compounds which we use in various natural product and medicinal chemistry programmes.

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