Journal
MOLECULAR DIVERSITY
Volume 15, Issue 1, Pages 41-68Publisher
SPRINGER
DOI: 10.1007/s11030-010-9258-1
Keywords
Isocyanide; Multicomponent reaction; MCR; IMCR; Iran
Categories
Funding
- Research Council of Shahid Beheshti University
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The aim of this review is to provide an overview of the contributions and recent advances made by Iranian scientists in the field of isocyanide-based reactions between 1999 and 2009. With over 100 publications during this period, Iranians are responsible for approximately 10% of all publications in the world involving isocyanide-based multicomponent reactions (IMCRs). Some important aspects of these IMCRs include the execution of reactions in green reaction mediums like water or ethanol, high atom economies, mild reaction conditions, high yields, and catalyst-free processes. On the other hand, in most of these reactions, new classes of heterocyclic compounds with potential biological and medicinal activities have been reported.
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