Journal
MOLECULAR DIVERSITY
Volume 13, Issue 3, Pages 385-387Publisher
SPRINGER
DOI: 10.1007/s11030-009-9122-3
Keywords
Cyclohexylisocyanide; 1,3-Indandione; One-pot; Three-component reaction
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Funding
- presidential office [87066/26]
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Aldehydes, 1,3-indandione and cyclohexylisocyanide undergo smooth coupling-cyclization in water to produce the corresponding 2-(cyclohexylamino)-3-aryl- indeno [1,2-b] furan-4-ones in good yields. Water was used as a solvent to avoid the use of other highly toxic and environmentally unfavorable solvents for this synthesis.
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