Journal
MOLECULAR CELL
Volume 43, Issue 2, Pages 161-163Publisher
CELL PRESS
DOI: 10.1016/j.molcel.2011.07.002
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Transcription elongation factor NusG/Spt5 spans the central cleft of RNA polymerase and functionally competes with transcription initiation factors. This work highlights the RNA polymerase clamp as a target for regulation and points to dynamic interactions between initiation and elongation machineries.
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