4.8 Editorial Material

A Role for Dormant Origins in Tumor Suppression

Journal

MOLECULAR CELL
Volume 41, Issue 5, Pages 495-496

Publisher

CELL PRESS
DOI: 10.1016/j.molcel.2011.02.014

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Funding

  1. Cancer Research UK [A7999, A7399] Funding Source: Medline

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In this issue of Molecular Cell, Kawabata et al. (2011) show that mice hypomorphic for the replication licensing protein Mcm4 show spontaneous DNA replication defects due to a lack of dormant origins, potentially explaining why these mice are cancer prone.

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