Journal
MOLECULAR CELL
Volume 41, Issue 1, Pages 5-7Publisher
CELL PRESS
DOI: 10.1016/j.molcel.2010.12.024
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In a recent issue of Molecular Cell, Kazanietz and colleagues (Sosa et al., 2010) show that P-Rex1, a Rac1 GEF, is overexpressed in ER+ and/or ErbB2+ breast cancers, suggesting that P-Rex1 might be a convergence node downstream of these receptors and an attractive therapeutic target.
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