Journal
MOLECULAR CELL
Volume 40, Issue 6, Pages 860-861Publisher
CELL PRESS
DOI: 10.1016/j.molcel.2010.12.014
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Funding
- NCI NIH HHS [R37 CA030490-26, R37 CA030490] Funding Source: Medline
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The copying of chromosomal DNA initiates from a single nucleoprotein assembly called the prereplication complex. New findings in a recent issue of Molecular Cell (Yardimci et al., 2010) reveal that this complex dissolves into two independent replisomes that move away from each other as DNA synthesis ensues.
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