4.8 Editorial Material

Dangerous Liaisons: Fanconi Anemia and Toxic Nonhomologous End Joining in DNA Crosslink Repair

Journal

MOLECULAR CELL
Volume 39, Issue 2, Pages 164-166

Publisher

CELL PRESS
DOI: 10.1016/j.molcel.2010.07.016

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Funding

  1. Intramural NIH HHS [ZIA BC010959-11, ZIA BC010283-21] Funding Source: Medline

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The proper choice of repair pathway is critical to tolerating various types of DNA damage. In a recent issue of Molecular Cell, Adamo et al. (2010), along with a second report (Pace et al., 2010), describe how the Fanconi anemia (FA) pathway is involved in preventing aberrant DNA repair. These studies suggest a potentially significant new opportunity for the treatment of FA.

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