Journal
MOLECULAR CELL
Volume 39, Issue 4, Pages 487-489Publisher
CELL PRESS
DOI: 10.1016/j.molcel.2010.08.006
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Funding
- NIGMS NIH HHS [R01 GM074917-05, R01 GM074917] Funding Source: Medline
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In this issue of Molecular Cell, Fachinetti et al. provide the first comprehensive map of replication termination sites (TERs) in Saccharomyces cerevisiae (Fachinetti et al., 2010). Strikingly, the majority of TERs are occupied by topoisomerase 2, which shields these regions against genomic instability.
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