Journal
MOLECULAR CELL
Volume 36, Issue 4, Pages 541-546Publisher
CELL PRESS
DOI: 10.1016/j.molcel.2009.10.019
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Funding
- NIGMS NIH HHS [R01 GM056663-10, R01 GM046498-20, R01 GM046498, R01 GM056663] Funding Source: Medline
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The C-terminal domain of RNA polymerase H's largest subunit undergoes dynamic phosphorylation during transcription, and the different phosphorylation patterns that predominate at each stage of transcription recruit the appropriate set of mRNA-processing and histone-modifying factors. Recent papers help to explain how the changes in CTD phosphorylation pattern are linked to the progression from initiation through elongation to termination.
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