Journal
MOLECULAR CELL
Volume 36, Issue 5, Pages 715-719Publisher
CELL PRESS
DOI: 10.1016/j.molcel.2009.11.030
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The linearity of eukaryotic chromosomes presents challenges to cells, as the presence of DNA ends poses problems for the DNA replication machinery and the cell's damage response systems. This year's Nobel Prize in Physiology or Medicine recognized groundbreaking studies establishing the telomere field as a crucial area of biomedical research.
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