Journal
SCIENCE CHINA-CHEMISTRY
Volume 58, Issue 5, Pages 793-809Publisher
SCIENCE PRESS
DOI: 10.1007/s11426-015-5370-5
Keywords
magnetic nanoparticles; biological detection; sensitivity; methods
Categories
Funding
- National Natural Science Foundation of China [2014M561073, 51173139]
- Program for Young Outstanding Scientists of Institute of Chemistry
- Chinese Academy of Science [Y41Z011]
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Magnetic nanoparticles have emerged as a powerful tool for magnetic resonance imaging, biodetection, drug delivery, and hyperthermia. This review focuses on the biological detection of magnetic nanoparticles as well as their physicochemical properties. Substantial progress in the sensitivity of detection has been made by developing variety of methods. Five applications of magnetic nanoparticles in biological detection are discussed in this review: magnetic separation, magnetic sensing, magnetic manipulation, magnetic catalysis, and signal enhancer for surface plasmon resonance (SPR). Finally, some future trends and perspectives in these research areas are outlined.
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