4.1 Article

Synthesis of LipidGreen2 and its application in lipid and fatty liver imaging

Journal

MOLECULAR BIOSYSTEMS
Volume 9, Issue 4, Pages 630-633

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3mb70022d

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Funding

  1. Ministry of Education, Science and Technology, Korea [2010-0019773]
  2. Ministry of Knowledge Economy, Korea [2012-10033674]
  3. National Research Foundation of Korea [2010-0019773] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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We have developed LipidGreen2, a second generation small molecule probe for lipid imaging. LipidGreen2 has a better fluorescence signal compared with the previous LipidGreen, and selectively stains neutral lipids in cells and fat deposits in live zebrafish. We also demonstrate the application of LipidGreen2 for detecting fatty liver.

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