4.1 Article

Site-selective labeling at Cys302 of aldehyde dehydrogenase unveils a selective mitochondrial stain

Journal

MOLECULAR BIOSYSTEMS
Volume 7, Issue 8, Pages 2375-2378

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1mb05137g

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Funding

  1. A*STAR (Agency for Science, Technology and Research, Singapore) Biomedical Research Council
  2. A*STAR SSCC [SSCC10/024]
  3. POSCO TJ Park

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A mitochondria-trackable fluorophore, CDy2, selectively labels Cys302 in the active site of mitochondrial aldehyde dehydrogenase (ALDH2).

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