Journal
MOLECULAR BIOSYSTEMS
Volume 6, Issue 11, Pages 2129-2132Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0mb00063a
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- BP Energy Biosciences Institute
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Glucose repression is one of the main limitations in mixed lignocellulosic sugar fermentation for cost-effective production of fuels and chemicals. Here we report a novel strategy to overcome glucose repression by co-expressing a cellobiose transporter and a beta-glucosidase in an engineered D-xylose-utilizing Saccharomyces cerevisiae strain. The resulting strain can simultaneously utilize cellobiose and D-xylose for ethanol production.
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