4.1 Article

Simultaneous glycoproteomics on the basis of structure using ion mobility-mass spectrometry

Journal

MOLECULAR BIOSYSTEMS
Volume 5, Issue 11, Pages 1298-1302

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b909745g

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Funding

  1. National Institutes of Health-NIDA [HHSN2712006775-63C]
  2. US Defense Threat Reduction Agency [HDTRA1-091-0013]
  3. Vanderbilt University College of Arts and Sciences
  4. Vanderbilt Institute of Chemical Biology
  5. American Society for Mass Spectrometry
  6. Waters Corp

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Simultaneous glycoproteomic characterization using rapid (mu s to ms) structural separations provided by ion mobility-mass spectrometry (IM-MS) is described. Advantages from using both ESI and MALDI ion sources are presented with future implications toward high throughput glycan and glycoconjugate characterization.

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