Journal
MOLECULAR BIOSYSTEMS
Volume 6, Issue 1, Pages 95-97Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b916228c
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- University of Maryland
- UM graduate research board
- NSF
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The identification of a suitable non-fluorescent molecule that can be oxidized by G-quadruplexes into a fluorescent product will be important for several fields such as bioanalyte sensing and cancer therapeutic discovery. Herein, we demonstrate that 2',7'-dichlorodihydrofluorescein diacetate is a superior reducing substrate for the fluorometric detection of bioanalytes using peroxidase-mimicking G-quadruplex DNAzymes.
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