Journal
MOLECULAR BIOLOGY REPORTS
Volume 38, Issue 2, Pages 1363-1366Publisher
SPRINGER
DOI: 10.1007/s11033-010-0238-4
Keywords
ROCK; Breast cancer; Metastasis
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Funding
- Chinese Academy of Sciences
- National Natural Science Foundation of China (NSFC)
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Metastasis is the predominant cause of death in most breast cancer patients. The molecular mechanisms underlying metastasis from primary tumors to distant organs are not clearly characterized. In this review, we depict the role of ROCK signaling in regulating cell motility and growth, and discuss the contribution of this signaling to breast cancer metastasis.
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