4.8 Article

K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac

Related references

Note: Only part of the references are listed.
Review Physiology

The force-from-lipid (FFL) principle of mechanosensitivity, at large and in elements

Jinfeng Teng et al.

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2015)

Article Multidisciplinary Sciences

Physical mechanism for gating and mechano sensitivity of the human TRAAK K+ channel

Stephen G. Brohawn et al.

NATURE (2014)

Article Multidisciplinary Sciences

Mechanosensitivity is mediated directly by the lipid membrane in TRAAK and TREK1 K+ channels

Stephen G. Brohawn et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Multidisciplinary Sciences

Feeling the hidden mechanical forces in lipid bilayer is an original sense

Andriy Anishkin et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Multidisciplinary Sciences

Ion permeation in K+ channels occurs by direct Coulomb knock-on

David A. Koepfer et al.

SCIENCE (2014)

Article Pharmacology & Pharmacy

Influence of the N Terminus on the Biophysical Properties and Pharmacology of TREK1 Potassium Channels

Emma L. Veale et al.

MOLECULAR PHARMACOLOGY (2014)

Article Multidisciplinary Sciences

Domain-swapped chain connectivity and gated membrane access in a Fab-mediated crystal of the human TRAAK K+ channel

Stephen G. Brohawn et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Biochemistry & Molecular Biology

Metabolic and thermal stimuli control K2P2.1 (TREK-1) through modular sensory and gating domains

Sviatoslav N. Bagriantsev et al.

EMBO JOURNAL (2012)

Article Biochemistry & Molecular Biology

Current trends in α-helical membrane protein crystallization: An update

Joanne L. Parker et al.

PROTEIN SCIENCE (2012)

Article Multidisciplinary Sciences

Crystal Structure of the Human K2P TRAAK, a Lipid- and Mechano-Sensitive K+ Ion Channel

Stephen G. Brohawn et al.

SCIENCE (2012)

Article Multidisciplinary Sciences

Crystal Structure of the Human Two-Pore Domain Potassium Channel K2P1

Alexandria N. Miller et al.

SCIENCE (2012)

Review Biochemistry & Molecular Biology

Molecular regulations governing TREK and TRAAK channel functions

Jacques Noel et al.

CHANNELS (2011)

Article Biochemistry & Molecular Biology

The pore structure and gating mechanism of K2P channels

Paula L. Piechotta et al.

EMBO JOURNAL (2011)

Article Biochemistry & Molecular Biology

Multiple modalities converge on a common gate to control K2P channel function

Sviatoslav N. Bagriantsev et al.

EMBO JOURNAL (2011)

Article Biochemical Research Methods

MolProbity: all-atom structure validation for macromolecular crystallography

Vincent B. Chen et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)

Article Biochemical Research Methods

XDS

Wolfgang Kabsch

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)

Article Biochemical Research Methods

Features and development of Coot

P. Emsley et al.

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)

Article Biochemical Research Methods

PHENIX: a comprehensive Python-based system for macromolecular structure solution

Paul D. Adams et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)

Review Physiology

Molecular Background of Leak K+ Currents: Two-Pore Domain Potassium Channels

Peter Enyedi et al.

PHYSIOLOGICAL REVIEWS (2010)

Article Biochemistry & Molecular Biology

PROMOTIF-A program to identify and analyze structural motifs in proteins

E. Gail Hutchinson et al.

PROTEIN SCIENCE (2010)

Review Pharmacology & Pharmacy

Research into the therapeutic roles of two-pore-domain potassium channels

Zeineb Es-Salah-Lamoureux et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2010)

Review Biophysics

Two-pore potassium channels in the cardiovascular system

Alison Gurney et al.

EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS (2009)

Article Biophysics

Gating the pore of potassium leak channels

Asi Cohen et al.

EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS (2009)

Article Multidisciplinary Sciences

Extracellular acidification exerts opposite actions on TREK1 and TREK2 potassium channels via a single conserved histidine residue

Guillaume Sandoz et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Biochemistry & Molecular Biology

Rationalizing α-helical membrane protein crystallization

Simon Newstead et al.

PROTEIN SCIENCE (2008)

Review Physiology

Up- and down-regulation of the mechano-gated K2P channel TREK-1 by PIP2 and other membrane phospholipids

Jean Chemin et al.

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2007)

Review Biochemistry & Molecular Biology

Inference of macromolecular assemblies from crystalline state

Evgeny Krissinel et al.

JOURNAL OF MOLECULAR BIOLOGY (2007)

Article Chemistry, Multidisciplinary

Phaser crystallographic software

Airlie J. McCoy et al.

JOURNAL OF APPLIED CRYSTALLOGRAPHY (2007)

Review Neurosciences

The neuronal background K-2P channels: focus on TREK1

Eric Honore

NATURE REVIEWS NEUROSCIENCE (2007)

Article Neurosciences

Deletion of the background potassium channel TREK-1 results in a depression-resistant phenotype

Catherine Heurteaux et al.

NATURE NEUROSCIENCE (2006)

Article Chemistry, Multidisciplinary

Insertion and assembly of membrane proteins via simulation

PJ Bond et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)

Article Biochemical Research Methods

Scaling and assessment of data quality

P Evans

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2006)

Article Pharmacology & Pharmacy

Inhibition of the human two-pore domain potassium channel, TREK-1, by fluoxetine and its metabolite norfluoxetine

LE Kennard et al.

BRITISH JOURNAL OF PHARMACOLOGY (2005)

Article Chemistry, Multidisciplinary

UCSF chimera - A visualization system for exploratory research and analysis

EF Pettersen et al.

JOURNAL OF COMPUTATIONAL CHEMISTRY (2004)