Journal
MOLECULAR BIOLOGY OF THE CELL
Volume 25, Issue 22, Pages 3486-3493Publisher
AMER SOC CELL BIOLOGY
DOI: 10.1091/mbc.E14-08-1306
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Funding
- National Institutes of Health [GM046383, GM107615]
- Research Foundation-Flanders
- Belgian American Educational Foundation
- Research Council of the Vrije Universiteit Brussel
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Trigger waves are a recurring biological phenomenon involved in transmitting information quickly and reliably over large distances. Well-characterized examples include action potentials propagating along the axon of a neuron, calcium waves in various tissues, and mitotic waves in Xenopus eggs. Here we use the FitzHugh-Nagumo model, a simple model inspired by the action potential that is widely used in physics and theoretical biology, to examine different types of trigger waves-spatial switches, pulses, and oscillations-and to show how they arise.
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