Related references
Note: Only part of the references are listed.Structural insights into Noonan/LEOPARD syndrome-related mutants of protein-tyrosine phosphatase SHP2 (PTPN11)
Wei Qiu et al.
BMC STRUCTURAL BIOLOGY (2014)
Structural and Mechanistic Insights into LEOPARD Syndrome-Associated SHP2 Mutations
Zhi-Hong Yu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
PTMScan Direct: Identification and Quantification of Peptides from Critical Signaling Proteins by Immunoaffinity Enrichment Coupled with LC-MS/MS
Matthew P. Stokes et al.
MOLECULAR & CELLULAR PROTEOMICS (2012)
Noonan syndrome gain-of-function mutations in NRAS cause zebrafish gastrulation defects
Vincent Runtuwene et al.
DISEASE MODELS & MECHANISMS (2011)
RAS signaling pathway mutations and hypertrophic cardiomyopathy: getting into and out of the thick of it
Bruce D. Gelb et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Rapamycin reverses hypertrophic cardiomyopathy in a mouse model of LEOPARD syndrome-associated PTPN11 mutation
Talita M. Marin et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Genetic Analyses of Integrin Signaling
Sara A. Wickstroem et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2011)
A Tissue-Specific Atlas of Mouse Protein Phosphorylation and Expression
Edward L. Huttlin et al.
CELL (2010)
RPTPα and PTPε signaling via Fyn/Yes and RhoA is essential for zebrafish convergence and extension cell movements during gastrulation
Mark van Eekelen et al.
DEVELOPMENTAL BIOLOGY (2010)
Phosphatase-Dependent and -Independent Functions of Shp2 in Neural Crest Cells Underlie LEOPARD Syndrome Pathogenesis
Rodney A. Stewart et al.
DEVELOPMENTAL CELL (2010)
Phosphorylation and localization of protein-zero related (PZR) in cultured endothelial cells
Ken-ichi Kusano et al.
ENDOTHELIUM-JOURNAL OF ENDOTHELIAL CELL RESEARCH (2008)
Noonan, Costello and cardio–facio–cutaneous syndromes: dysregulation of the Ras–MAPK pathway
William E. Tidyman et al.
EXPERT REVIEWS IN MOLECULAR MEDICINE (2008)
Noonan syndrome-associated SHP-2/Ptpn11 mutants enhance SIRPα and PZR tyrosyl phosphorylation and promote adhesion-mediated ERK activation
Seda Eminaga et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Signaling networks assembled by oncogenic EGFR and c-Met
Ailan Guo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer
Klarisa Rikova et al.
CELL (2007)
Shp2 knockdown and Noonan/LEOPARD mutant Shp2-induced gastrulation defects
Chris Jopling et al.
PLOS GENETICS (2007)
The murine ortholog of the SHP-2 binding molecule, PZR accelerates cell migration on fibronectin and is expressed in early embryo formation
Maria G. Roubelakis et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2007)
p53 activation by knockdown technologies
Mara E. Robu et al.
PLOS GENETICS (2007)
Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry
Joshua E. Elias et al.
NATURE METHODS (2007)
Structural and functional effects of disease-causing amino acid substitutions affecting residues Ala72 and Glu76 of the protein tyrosine phosphatase SHP-2
Gianfranco Bocchinfuso et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2007)
Protein tyrosine phosphatase function: the substrate perspective
Tony Tiganis et al.
BIOCHEMICAL JOURNAL (2007)
Noonan syndrome and related disorders: dysregulated RAS-mitogen activated protein kinase signal transduction
Bruce D. Gelb et al.
HUMAN MOLECULAR GENETICS (2006)
SHP-2 activates signaling of the nuclear factor of activated T cells to promote skeletal muscle growth
Mara Fornaro et al.
JOURNAL OF CELL BIOLOGY (2006)
A probability-based approach for high-throughput protein phosphorylation analysis and site localization
Sean A. Beausoleil et al.
NATURE BIOTECHNOLOGY (2006)
Reduced phosphatase activity of SHP-2 in LEOPARD syndrome: Consequences for PI3K binding on Gab1
Nadine Hanna et al.
FEBS LETTERS (2006)
PTPN11 (Shp2) mutations in LEOPARD syndrome have dominant negative, not activating, effects
MI Kontaridis et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
An Shp2/SFK/Ras/Erk signaling pathway controls trophoblast stem cell survival
WT Yang et al.
DEVELOPMENTAL CELL (2006)
Diversity and functional consequences of germline and somatic PTPN11 mutations in human disease
M Tartaglia et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2006)
Fyn/Yes and non-canonical Wnt signalling converge on RhoA in vertebrate gastrulation cell movements
C Jopling et al.
EMBO REPORTS (2005)
Prognostic, therapeutic, and mechanistic implications of a mouse model of leukemia evoked by Shp2 (PTPN11) mutations
MG Mohi et al.
CANCER CELL (2005)
Immunoaffinity profiling of tyrosine phosphorylation in cancer cells
J Rush et al.
NATURE BIOTECHNOLOGY (2005)
Shp2 regulates Src family kinase activity and Ras/Erk activation by controlling Csk recruitment
SQ Zhang et al.
MOLECULAR CELL (2004)
Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation
T Araki et al.
NATURE MEDICINE (2004)
SHP-2 positively regulates myogenesis by coupling to the rho GTPase signaling pathway
MI Kontaridis et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling
BG Neel et al.
TRENDS IN BIOCHEMICAL SCIENCES (2003)
Redox-regulated rotational coupling of receptor protein-tyrosine phosphatase α dimers
T van der Wijk et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Identification of a variant form of PZR lacking immunoreceptor tyrosine-based inhibitory motifs
RX Zhao et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Novel mesenchymal and haematopoietic cell isoforms of the SHP-2 docking receptor, PZR: identification, molecular cloning and effects on cell migration
ACW Zannettino et al.
BIOCHEMICAL JOURNAL (2003)
Cell surface glycoprotein PZR is a major mediator of concanavalin A-induced cell signaling
RX Zhao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome
M Tartaglia et al.
NATURE GENETICS (2001)
Dissecting the interaction of SHP-2 with PZR, an immunoglobulin family protein containing immunoreceptor tyrosine-based inhibitory motifs
RX Zhao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Share Paper
