Related references
Note: Only part of the references are listed.Targeting RNA Polymerase I with an Oral Small Molecule CX-5461 Inhibits Ribosomal RNA Synthesis and Solid Tumor Growth
Denis Drygin et al.
CANCER RESEARCH (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Identification of DHX33 as a Mediator of rRNA Synthesis and Cell Growth
Yandong Zhang et al.
MOLECULAR AND CELLULAR BIOLOGY (2011)
Transcription by RNA polymerase III: more complex than we thought
Robert J. White
NATURE REVIEWS GENETICS (2011)
The RNA Polymerase I Transcription Machinery: An Emerging Target for the Treatment of Cancer
Denis Drygin et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY (2010)
ARF Suppresses Tumor Angiogenesis through Translational Control of VEGFA mRNA
Hiroyuki Kawagishi et al.
CANCER RESEARCH (2010)
The ARF Tumor Suppressor Controls Ribosome Biogenesis by Regulating the RNA Polymerase I Transcription Factor TTF-I
Frederic Lessard et al.
MOLECULAR CELL (2010)
Anticancer Activity of CX-3543: A Direct Inhibitor of rRNA Biogenesis
Denis Drygin et al.
CANCER RESEARCH (2009)
Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
Ji Luo et al.
CELL (2009)
Nucleolus, ribosomes, and cancer
Lorenzo Montanaro et al.
AMERICAN JOURNAL OF PATHOLOGY (2008)
RNA polymerases I and III, non-coding RNAs and cancer
Robert J. White
TRENDS IN GENETICS (2008)
Is ribosome synthesis controlled by Pol I transcription?
Stephane Chedin et al.
CELL CYCLE (2007)
Human tumor suppressor p14ARF negatively regulates rRNA transcription and inhibits UBF1 transcription factor phosphorylation
O. Ayrault et al.
ONCOGENE (2006)
Nascent pre-rRNA overexpression correlates with an adverse prognosis in alveolar rhabdomyosarcoma
Daniel Williamson et al.
GENES CHROMOSOMES & CANCER (2006)
The transcriptional activity of RNA polymerase I is a key determinant for the level of all ribosome components
Arnaud Laferte et al.
GENES & DEVELOPMENT (2006)
Growth factor signaling regulates elongation of RNA polymerase I transcription in mammals via UBF phosphorylation and r-chromatin remodeling
V Stefanovsky et al.
MOLECULAR CELL (2006)
PTEN represses RNA polymerase I transcription by disrupting the SL1 complex
C Zhang et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Genetic inactivation of the transcription factor TIF-IA leads to nucleolar disruption, cell cycle arrest, and p53-mediated apoptosis
XJ Yuan et al.
MOLECULAR CELL (2005)
The NF1 tumor suppressor critically regulates TSC2 and mTOR
CM Johannessen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Proteomic analysis reveals hyperactivation of the mammalian target of rapamycin pathway in neurofibromatosis 1-associated human and mouse brain tumors
B Dasgupta et al.
CANCER RESEARCH (2005)
Myc-dependent regulation of ribosomal RNA synthesis during Drosophila development
SS Grewal et al.
NATURE CELL BIOLOGY (2005)
c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I
C Grandori et al.
NATURE CELL BIOLOGY (2005)
mTOR-dependent activation of the transcription factor TIMA links rRNA synthesis to nutrient availability
C Mayer et al.
GENES & DEVELOPMENT (2004)
Nucleolar size and activity are related to pRb and p53 status in human breast cancer
D Treré et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2004)
Human Arf tumor suppressor specifically interacts with chromatin containing the promoter of rRNA genes
O Ayrault et al.
ONCOGENE (2004)
mTOR-Dependent regulation of ribosomal gene transcription requires S6K1 and is mediated by phosphorylation of the carboxy-terminal activation domain of the nucleolar transcription factor UBF
KM Hannan et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Disruption of the nucleolus mediates stabilization of p53 in response to DNA damage and other stresses
CP Rubbi et al.
EMBO JOURNAL (2003)
Life on a planet of its own: regulation of RNA polymerase I transcription in the nucleolus
I Grummt
GENES & DEVELOPMENT (2003)
ERK-dependent phosphorylation of the transcription initiation factor TIF-IA is required for RNA polymerase I transcription and cell growth
J Zhao et al.
MOLECULAR CELL (2003)
Tumor suppressor ARF degrades B23, a nucleolar protein involved in ribosome biogenesis and cell proliferation
K Itahana et al.
MOLECULAR CELL (2003)
Targeting ras signalling pathways in cancer therapy
J Downward
NATURE REVIEWS CANCER (2003)
Phosphorylation of UBF at serine 388 is required for interaction with RNA polymerase I and activation of rDNA transcription
R Voit et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
An immediate response of ribosomal transcription to growth factor stimulation in mammals is mediated by ERK phosphorylation of UBF
VY Stefanovsky et al.
MOLECULAR CELL (2001)
p53-independent functions of the p19ARF tumor suppressor
JD Weber et al.
GENES & DEVELOPMENT (2000)
Repression of RNA polymerase I transcription by the tumor suppressor p53
WG Zhai et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Understanding Ras: 'it ain't over 'til it's over'
JM Shields et al.
TRENDS IN CELL BIOLOGY (2000)
Share Paper
