Related references
Note: Only part of the references are listed.OM-RCA-01, a novel humanized monoclonal antibody targeting fibroblast growth factor receptor 1, in renal cell carcinoma model
Ilya Tsimafeyeu et al.
INVESTIGATIONAL NEW DRUGS (2013)
A Highly Potent and Specific MET Therapeutic Protein Antagonist with Both Ligand-Dependent and Ligand-Independent Activity
Shane A. Olwill et al.
MOLECULAR CANCER THERAPEUTICS (2013)
Resistance after Chronic Application of the HDAC-Inhibitor Valproic Acid Is Associated with Elevated Akt Activation in Renal Cell Carcinoma In Vivo
Eva Juengel et al.
PLOS ONE (2013)
Hypoxia-inducible Factor 1 regulated ARC expression mediated hypoxia induced inactivation of the intrinsic death pathway in p53 deficient human colon cancer cells
Jin-e Ao et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)
An Optimized Activity-Based Probe for the Study of Caspase-6 Activation
Laura E. Edgington et al.
CHEMISTRY & BIOLOGY (2012)
State of the Science: An Update on Renal Cell Carcinoma
Eric Jonasch et al.
MOLECULAR CANCER RESEARCH (2012)
Expression of ARC (apoptosis repressor with caspase recruitment domain), an antiapoptotic protein, is strongly prognostic in AML
Bing Z. Carter et al.
BLOOD (2011)
High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq
Johannes Schoedel et al.
BLOOD (2011)
Apoptosis Inhibitor ARC Promotes Breast Tumorigenesis, Metastasis, and Chemoresistance
Christina M. Medina-Ramirez et al.
CANCER RESEARCH (2011)
A Critical Role for the Protein Apoptosis Repressor With Caspase Recruitment Domain in Hypoxia-Induced Pulmonary Hypertension
Ari L. Zaiman et al.
CIRCULATION (2011)
Apoptosis repressor with caspase recruitment domain, a multifunctional modulator of cell death
Agnieszka H. Ludwig-Galezowska et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2011)
VHL loss in renal cell carcinoma leads to up-regulation of CUB domain-containing protein 1 to stimulate PKCδ-driven migration
Olga V. Razorenova et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
USP10 Regulates p53 Localization and Stability by Deubiquitinating p53
Jian Yuan et al.
CELL (2010)
Induction of the Apoptosis Inhibitor ARC by Ras in Human Cancers
Lily Wu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Regulation of the Histone Demethylase JMJD1A by Hypoxia-Inducible Factor 1 alpha Enhances Hypoxic Gene Expression and Tumor Growth
Adam J. Krieg et al.
MOLECULAR AND CELLULAR BIOLOGY (2010)
Apoptosis Repressor with Caspase Recruitment Domain Contributes to Chemotherapy Resistance by Abolishing Mitochondrial Fission Mediated by Dynamin-Related Protein-1
Jian-Xun Wang et al.
CANCER RESEARCH (2009)
Patterns of Gene Expression and Copy-Number Alterations in von-Hippel Lindau Disease-Associated and Sporadic Clear Cell Carcinoma of the Kidney
Rameen Beroukhim et al.
CANCER RESEARCH (2009)
Suppression of Hypoxia-inducible Factor 2α Restores p53 Activity via Hdm2 and Reverses Chemoresistance of Renal Carcinoma Cells
Andrew M. Roberts et al.
CANCER RESEARCH (2009)
The role of VHL in clear-cell renal cell carcinoma and its relation to targeted therapy
Peter E. Clark
KIDNEY INTERNATIONAL (2009)
Regulation of Oxygen Homeostasis by Hypoxia-Inducible Factor 1
Gregg L. Semenza
PHYSIOLOGY (2009)
HIF-α Effects on c-Myc Distinguish Two Subtypes of Sporadic VHL-Deficient Clear Cell Renal Carcinoma
John D. Gordan et al.
CANCER CELL (2008)
Inhibition of endoplasmic reticulum stress-induced apoptosis of melanoma cells by the ARC protein
Li Hua Chen et al.
CANCER RESEARCH (2008)
Expression and modification of ARC (apoptosis repressor with a CARD domain) is distinctly regulated by oxidative stress in cancer cells
Yi-Qiang Zhang et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2008)
p53 initiates apoptosis by transcriptionally targeting the antiapoptotic protein ARC
Yu-Zhen Li et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Regulation of p53 tetramerization and nuclear export by ARC
Roger S. -Y. Foo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Secreted frizzled-related protein 1 loss contributes to tumor phenotype of clear cell renal cell carcinoma
Michelle L. Gumz et al.
CLINICAL CANCER RESEARCH (2007)
Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype:: Lessons from recent developments in the IARC TP53 database
Audrey Petitjean et al.
HUMAN MUTATION (2007)
Disease-specific genomic analysis: identifying the signature of pathologic biology
Monica Nicolau et al.
BIOINFORMATICS (2007)
The hypoxia-inducible factor 2α N-terminal and C-terminal transactivation domains cooperate to promote renal tumorigenesis in vivo
Qin Yan et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Ubiquitination and degradation of the anti-apoptotic protein ARC by MDM2
Roger S. -Y. Foo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
The apoptosis inhibitor ARC undergoes ubiquitin-proteasomal-mediated degradation in response to death stimuli - Identification of a degradation-resistant mutant
Young-Jae Nam et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Hypoxia-inducible factors in the kidney
Volker H. Haase
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2006)
Gene expression profiling predicts survival in conventional renal cell carcinoma
HJ Zhao et al.
PLOS MEDICINE (2006)
Small molecules that reactivate p53 in renal cell carcinoma reveal a NF-κB-dependent mechanism of p53 suppression in tumors
KV Gurova et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
p53 regulation and function in renal cell carcinoma
HE Warburton et al.
CANCER RESEARCH (2005)
ARC, an apoptosis suppressor limited to terminally differentiated cells, is induced in human breast cancer and confers chemo- and radiation-resistance
I Mercier et al.
CELL DEATH AND DIFFERENTIATION (2005)
Virus-based reporter systems for monitoring transcriptional activity of hypoxia-inducible factor 1
OV Razorenova et al.
GENE (2005)
Apoptosis repressor with caspase recruitment domain (ARC) is expressed in cancer cells and localizes to nuclei
M Wang et al.
FEBS LETTERS (2005)
VHL expression in renal cell carcinoma sensitizes to bortezomib (PS-341) through an NF-κB-dependent mechanism
JB An et al.
ONCOGENE (2005)
p53 pathway in renal cell carcinoma is repressed by a dominant mechanism
KV Gurova et al.
CANCER RESEARCH (2004)
Gene expression in the normal adult human kidney assessed by complementary DNA microarray
JPT Higgins et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
Inhibition of both the extrinsic and intrinsic death pathways through nonhomotypic death-fold interactions
YJ Nam et al.
MOLECULAR CELL (2004)
Apoptosis repressor with caspase recruitment domain protects against cell death by interfering with Bax activation
ÅB Gustafsson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Previously unidentified changes in renal cell carcinoma gene expression identified by parametric analysis of microarray data
ME Lenburg et al.
BMC CANCER (2003)
Inhibition of HIF2 alpha is sufficient to suppress pVHL-defective tumor growth
K Kondo et al.
PLOS BIOLOGY (2003)
TAT protein transduction into isolated perfused hearts -: TAT-apoptosis repressor with caspase recruitment domain is cardioprotective
ÅB Gustafsson et al.
CIRCULATION (2002)
Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein
K Kondo et al.
CANCER CELL (2002)
The apoptotic regulatory protein ARC (apoptosis repressor with caspase recruitment domain) prevents oxidant stress-mediated cell death by preserving mitochondrial function
M Neuss et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)