Journal
MOLECULAR AND BIOCHEMICAL PARASITOLOGY
Volume 195, Issue 2, Pages 107-114Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.molbiopara.2014.06.001
Keywords
Plasmodium falciparum; Antimalarial resistance; Drug selection; Genetics
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Funding
- Bill & Melinda Gates Foundation, World Wide Antimalarial Resistance Network
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The worlds of basic scientists and those involved in treating patients and making public health decisions do not always intersect. Yet, assuring that when patients are treated, they are efficiently and completely cured, and that public health decisions are based on solid evidence requires a broad foundation of up to date basic research. Research on the malaria parasite, Plasmodium falciparum provides a useful illustration of the role that basic scientific studies have played in the very long relationship between humans and this deadly parasite. Drugs have always been a principal tool in malaria treatment. The ongoing struggle between evolution of resistance to antimalarials by the parasite and public health responses is used here as an illustration of the key contributions of basic scientists to this long history. (C) 2014 Published by Elsevier B.V.
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