Journal
MODERN PATHOLOGY
Volume 24, Issue -, Pages S66-S77Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/modpathol.2010.127
Keywords
classification; endocrine tumor; molecular genetics; pancreas; predictive markers; staging
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The endocrine cells of the pancreas and their related cells throughout the gastrointestinal tract give rise to a variety of tumors that pose a diagnostic challenge. There has been progress in understanding their histogenesis, morphology, immunohistochemistry, molecular biology and classifications. This review will focus on nomenclature/terminology, classification, the role of immunohistochemistry, molecular advances, including genetic predisposition, and potential therapeutic targets to define the role of pathology in the application of prognostic and predictive markers for this disease. Modern Pathology (2011) 24, S66-S77; doi:10.1038/modpathol.2010.127
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