Journal
MITOCHONDRION
Volume 19, Issue -, Pages 282-288Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.mito.2014.02.008
Keywords
Mitochondria; Cytoplasmic male sterility (CMS); Restoration of fertility (Rf); Pentatricopeptide repeat (PPR); Restoration of fertility complex (RFC)
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Funding
- National Natural Science Foundation of China [31371698]
- National High Tech Research and Development Project [2011AA101101]
- National Key Project for Research on Transgenic Plant [2011ZX08010]
- Special Financial Grant from the China Postdoctoral Science Foundation [2013T60744]
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Mitochondria are essential organelles in cells not only because they supply over 90% of the cell's energy but also because their dysfunction is associated with disease. Owing to the importance of mitochondria, there are many questions about mitochondria that must be answered. Cytoplasmic male sterility (CMS) is a mysterious natural phenomenon, and the mechanism of the origin of CMS is unknown. Despite successful utilization of CMS and restoration of fertility (Rf) in practice, the underlying mechanisms of these processes remain elusive. This review summarizes the genes involved in CMS and Rf, with a special focus on recent studies reporting the mechanisms of the CMS and Rf pathways, and concludes with potential working models. (C) 2014 Elsevier B.V. and Mitochondria Research Society. All rights reserved.
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