Journal
MINI-REVIEWS IN ORGANIC CHEMISTRY
Volume 5, Issue 1, Pages 47-52Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/157019308783498188
Keywords
enzymatic ligation; sortase; proteins; peptides; peptide nucleic acids
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The chemical synthesis of proteins, as well as the modification of expressed proteins, requires highly selective reactions. Ligation methods offer feasible tools for this purpose. This mini-review focuses on enzymatic methods for protein ligation; in particular, on the use of the transpeptidase sortase.
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