4.5 Review

Caffeic Acid, A Versatile Pharmacophore: An Overview

Journal

MINI-REVIEWS IN MEDICINAL CHEMISTRY
Volume 11, Issue 8, Pages 695-713

Publisher

BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/138955711796268750

Keywords

Caffeic acid; anticancer; antioxidant; anti-inflammatory; integrase inhibitors; structure-activity relationships

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The caffeic acid scaffold, which is abundant in nature, is extremely versatile and is found in a number of biologically active molecules. The purpose of this review is to provide an overview of the pharmacological activity of synthetic caffeic acid analogs including recent reports of anti-inflammatory, anti-cancer, and antiviral activities of these compounds.

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