Journal
MINI-REVIEWS IN MEDICINAL CHEMISTRY
Volume 9, Issue 10, Pages 1147-1158Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/138955709789055243
Keywords
Antimicrobial susceptibility; ciprofloxacin; fluoroquinolones; focal infection; levofloxacin; moxifloxacin; oral infection; oral pathogens
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This article reviews the characteristics of the main fluoroquinolones used in dentistry ( ciprofloxacin, levofloxacin and moxifloxacin), including pharmacokinetic/pharmacodynamic parameters, susceptibility profiles of oral bacteria and clinical trials on their efficacy in dental practice. It seems that some of these antibiotics might represent a safe alternative in patients with allergy, intolerance, or lack of response to beta-lactams.
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