Journal
MINI-REVIEWS IN MEDICINAL CHEMISTRY
Volume 9, Issue 1, Pages 70-80Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/138955709787001802
Keywords
MicroRNA; miRNA; oncomirs; cancer biology; molecular targets; anticancer therapeutics
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Deregulation of microRNA ( miRNA) promotes carcinogenesis, as these molecules can act as oncogenes or tumor suppressor genes. Here we provide an overview of miRNA biology, discuss the most recent findings on miRNA and cancer development/progression, and report on how tumor-related miRNAs (oncomirs) are being used to develop novel cancer specific therapeutic approaches.
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