4.5 Review

Novel Perspectives in Celiac Disease Therapy

Journal

MINI-REVIEWS IN MEDICINAL CHEMISTRY
Volume 9, Issue 3, Pages 359-367

Publisher

BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1389557510909030359

Keywords

Celiac disease; gluten; immunity; permeability; therapy; intestinal microbiota; probiotics

Funding

  1. Spanish Ministry of Science and Innovation [AGL2007-66126C03-01/ALI, Fun-C-Food CSD2007-00063]

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Currently the only treatment for celiac disease is adherence to a strict gluten-free diet; however, compliance with this diet is complex and other alternatives are called for. Herein, we review recent developments in the design of novel therapeutic strategies to counteract the pathogenic effects of the interactions between gluten peptides and their specific biological targets.

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