Journal
MINI-REVIEWS IN MEDICINAL CHEMISTRY
Volume 9, Issue 3, Pages 340-358Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1389557510909030340
Keywords
Microwave; dielectric heating; combinatorial chemistry; medicinal chemistry; heterocycles; peptides; peptidomimetic
Categories
Ask authors/readers for more resources
The interest in the microwave assisted organic synthesis has been growing during the recent years. It results from an increasing knowledge of fundamentals of the dielectric heating theory, availability of an equipment designed especially for the laboratory use as well as the discovery of the special techniques of the microwave syntheses. The efficiency of microwave flash-heating chemistry in dramatically reducing reaction times (reduced from days and hours to minutes and seconds) has recently been proven in several different fields of organic chemistry and this aspect is of great importance in high-speed combinatorial and medicinal chemistry. In this contribution, the current state of the art is summarized providing examples of the most recent applications in the field of microwave assisted synthesis of biologically active compounds both in heterocyclic and in peptide and peptidomimetic optimization.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available