Journal
MINI-REVIEWS IN MEDICINAL CHEMISTRY
Volume 8, Issue 13, Pages 1395-1406Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/138955708786369582
Keywords
Antioxidant; calorie restriction; estrogen; free radical; glutathione; oxidation; oxidative stress; therapy
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Funding
- NIGMS NIH HHS [R25 GM060655-01] Funding Source: Medline
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Alzheimer disease treatment has yet to yield a successful therapy that addresses the source of the damage found in brains. Of the varied proposed theories of AD etiology, reactive oxygen species (ROS) generation is cited as a common factor. Efforts to reduce the pathology associated with ROS via antioxidants therefore offer new hope to patients suffering from this devastative disease.
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