Journal
SCHIZOPHRENIA RESEARCH
Volume 161, Issue 1, Pages 94-101Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.schres.2014.04.040
Keywords
Multiple sclerosis; Disease-modifying treatments; Neuroprotection; Repair; Neuroimaging
Categories
Funding
- Fondazione Italiana Sclerosi Multipla [FISM cod. 2013/B/7]
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Multiple sclerosis is the leading nontraumatic cause of neurologic disability in young adults. The need to prevent neurodegeneration and promote repair in multiple sclerosis (MS) has gained increasing interest in the last decade leading to the search and development of pharmacological agents and non-pharmacologic strategies able to target not only the inflammatory but also the neurodegenerative component of the disease. This paper will provide an overview of the therapeutics currently employed in MS, with a focus on their potential neuroprotective effects and on the MRI methods employed to detect and monitor in-vivo neuroprotection and repair and the relevance of this information to schizophrenia investigation and treatment. (C) 2014 Elsevier B.V. All rights reserved.
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