Journal
MICROPOROUS AND MESOPOROUS MATERIALS
Volume 188, Issue -, Pages 86-92Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.micromeso.2014.01.010
Keywords
MCM-41; Mesoporous materials; Magnetic-target; Nanocarrier; Drug delivery
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Funding
- Fundament of the Bureau of Education, Hunan Province [07C669]
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An MCM-41 type magnetic cylindrical ordered mesoporous silicon dioxide (M-COMSD) nanocarrier for targeted drug delivery has been synthesised. Pharmaceutical drug molecules have been loaded into the mesoporous framework of the M-COMSD. In vitro (Hale cells) and in vivo (mice) drug storage and release experiments of the nanocarrier have been performed. The results of the M-COMSD system demonstrate that this material could play a significant role in developing a new generation of controlled-release nanocarriers. (C) 2014 Elsevier Inc. All rights reserved.
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