Journal
MICROFLUIDICS AND NANOFLUIDICS
Volume 10, Issue 4, Pages 889-897Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s10404-010-0722-0
Keywords
Microfluidic; Diffusion micromixer; Time resolved; Infrared spectroscopy
Funding
- COMET Competence Center of the Austrian Government
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We present a horizontal multi-lamination micromixer with specially wedge shaped vertical fluid inlets for fast and highly uniform fluid mixing in the low millisecond range. The four-layer laminar flow is created by a fluidic distribution network, reducing the amount of fluid connectors to the macroscopic world to two. All the geometries of the channel inlets and the distribution network were optimized for low flow rates and hence for low sample consumption using CFD simulations. The device materials applied feature low absorption in the mid-infrared (wavelength 3--10 mu m) allowing to use this device for time resolved infrared spectroscopy. The micromixer itself can be built by silicon micromachining techniques without the need of complicated fabrication steps. Due to a transparent calcium fluoride cover optical measurements are possible as well which were used to characterize the device. Mixing times in the range of 1 ms with optical color measurements of aqueous solutions and with time resolved infrared measurement of the proton exchange reaction of H(2)O and D(2)O are achieved.
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