Journal
MICROFLUIDICS AND NANOFLUIDICS
Volume 6, Issue 1, Pages 53-62Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s10404-008-0296-2
Keywords
Magnetic particles; Micro-coils; Trapping; Capture radius
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This paper presents an efficient technique for trapping of magnetic particles in confined spatial locations using customized designs of micro-coils (MCs). Large magnetic field gradients of up to 20 T/mm and large magnetic forces in the range of 10(-8) Newton on magnetic particles with diameter of 1 mu m have been achieved using MCs with several planar geometrical configurations. A large magnetic field gradient is generated and enhanced by two structural parameters: the small width and high aspect ratio of each single conductor and the ferromagnetic pillars positioned at high-flux density locations. This arrangement creates very steep magnetic potential wells, in particular at the vicinity of the pillars. The system allowed capturing of suspended magnetic particles as far as 1,000 mu m from the center of the device. Magnetic particles/cells have been trapped and confined in single and in arrays of deep magnetic potential wells corresponding to the MCs configuration.
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