Related references
Note: Only part of the references are listed.Advances in IL-21 biology - enhancing our understanding of human disease
Stuart G. Tangye
CURRENT OPINION IN IMMUNOLOGY (2015)
Treatment of IL-21R-Fc control autoimmune arthritis via suppression of STAT3 signal pathway mediated regulation of the Th17/Treg balance and plasma B cells
Jun-Geol Ryu et al.
IMMUNOLOGY LETTERS (2015)
Interleukin-21: a double-edged sword with therapeutic potential
Rosanne Spolski et al.
NATURE REVIEWS DRUG DISCOVERY (2014)
Interleukin-21 Receptor Deficiency Increases the Initial Toll-like Receptor 2 Response but Protects Against Joint Pathology by Reducing Th1 and Th17 Cells During Streptococcal Cell Wall Arthritis
Renoud J. Marijnissen et al.
ARTHRITIS & RHEUMATOLOGY (2014)
Interleukin-6 Receptor Blockade Selectively Reduces IL-21 Production by CD4 T Cells and IgG4 Autoantibodies in Rheumatoid Arthritis
Gustavo Carbone et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2013)
Rheumatoid arthritis: still a chronic disease
Pierre Miossec
LANCET (2013)
Serum IL-6 and IL-21 are associated with markers of B cell activation and structural progression in early rheumatoid arthritis: results from the ESPOIR cohort
Jacques-Eric Gottenberg et al.
ANNALS OF THE RHEUMATIC DISEASES (2012)
Interleukin-21 promotes osteoclastogenesis in humans with rheumatoid arthritis and in mice with collagen-induced arthritis
Seung-Ki Kwok et al.
ARTHRITIS AND RHEUMATISM (2012)
Brief Report: Inhibition of interleukin-6 function corrects Th17/Treg cell imbalance in patients with rheumatoid arthritis
Maxime Samson et al.
ARTHRITIS AND RHEUMATISM (2012)
Increasing levels of circulating Th17 cells and interleukin-17 in rheumatoid arthritis patients with an inadequate response to anti-TNF-alpha therapy
Der-Yuan Chen et al.
ARTHRITIS RESEARCH & THERAPY (2011)
Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis
Beatrix Bartok et al.
IMMUNOLOGICAL REVIEWS (2010)
Interleukin-21: Basic biology and implications for cancer and autoimmunity
Rosanne Spolski et al.
ANNUAL REVIEW OF IMMUNOLOGY (2008)
The Yin and Yang of interleukin-21 in allergy, autoimmunity and cancer
Rosanne Spolski et al.
CURRENT OPINION IN IMMUNOLOGY (2008)
Evidence that cytokines play a role in rheumatoid arthritis
Fionula M. Brennan et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
Neutralizing IL-21 and IL-15 inhibits pro-inflammatory cytokine production in rheumatoid arthritis
A. K. Andersson et al.
SCANDINAVIAN JOURNAL OF IMMUNOLOGY (2008)
Essential autocrine regulation by IL-21 in the generation of inflammatory T cells
Roza Nurieva et al.
NATURE (2007)
Blockade of the interleukin-21/interleukin-21 receptor pathway ameliorates disease in animal models of rheumatoid arthritis
Deborah A. Young et al.
ARTHRITIS AND RHEUMATISM (2007)
The fibroblast-like synovial cell in rheumatoid arthritis: a key player in inflammation and joint destruction
A Mor et al.
CLINICAL IMMUNOLOGY (2005)
Targeting interleukin-15 in patients with rheumatoid arthritis - A proof-of-concept study
B Baslund et al.
ARTHRITIS AND RHEUMATISM (2005)
Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function
R Zeng et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Interleukin-21: A modulator of lymphoid proliferation, apoptosis and differentiation
WJ Leonard et al.
NATURE REVIEWS IMMUNOLOGY (2005)
Expression of interleukin-21 receptor, but not interleukin-21, in synovial fibroblasts and synovial macrophages of patients with rheumatoid arthritis
A Jüngel et al.
ARTHRITIS AND RHEUMATISM (2004)
Regulation of metalloproteinases and NF-κB activation in rabbit synovial fibroblasts via E prostaglandins and Erk:: contrasting effects of nabumetone and 6MNA
MH Pillinger et al.
BRITISH JOURNAL OF PHARMACOLOGY (2004)
IL-17 induces production of IL-6 and IL-8 in rheumatoid arthritis synovial fibroblasts via NF-kappa B- and PI3-kinase/Akt-dependent pathways
SY Hwang et al.
ARTHRITIS RESEARCH & THERAPY (2004)
In vivo selective inhibition of mitogen-activated protein kinase kinase 1/2 in rabbit experimental osteoarthritis is associated with a reduction in the development of structural changes
JP Pelletier et al.
ARTHRITIS AND RHEUMATISM (2003)
Evolving concepts of rheumatoid arthritis
GS Firestein
NATURE (2003)
Cutting edge:: The common γ-chain is an indispensable subunit of the IL-21 receptor complex
H Asao et al.
JOURNAL OF IMMUNOLOGY (2001)
Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function
J Parrish-Novak et al.
NATURE (2000)
Cloning of a type I cytokine receptor most related to the IL-2 receptor β chain
K Ozaki et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)