A glassy carbon electrode modified with porous gold nanosheets for simultaneous determination of dopamine and acetaminophen

Porous gold nanosheets modified glassy carbon electrode (GCE) was facilely prepared by one-step electrodeposition, using N-methylimidazole as a growth-directing agent. The porous gold nanosheets modified GCE was characterized by scanning electron microscopy, transmission electron microscopy, and X-ray diffraction spectroscopy. The modified electrode displayed improved sensitivity for individual and simultaneous differential pulse voltammetric determination of dopamine (DA; at 180 mV) and acetaminophen (AC; at 450 mV vs. Ag/AgCl) even in the presence of ascorbic acid. The oxidation peak currents linearly increased with the concentrations of DA and AC in the ranges from 2.0 to 298.0 mu M and 3.0 to 320.0 mu M, respectively, and the detection limits are 0.28 mu M for DA and 0.23 mu M for AC. The relative standard deviations (n = 20) are 1.5 % for DA and 0.4 % for AC.