Journal
MICROCHIMICA ACTA
Volume 180, Issue 3-4, Pages 161-186Publisher
SPRINGER WIEN
DOI: 10.1007/s00604-012-0923-1
Keywords
Non-enzymatic; Glucose; Electrochemical sensors
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Funding
- National Natural Science Foundation of China [20901003, 20971003, 21073001, 21005001]
- Chinese Ministry of Education [209060]
- Anhui Provincial Natural Science Foundation [1208085QB28]
- Natural Science Foundation of Anhui [KJ2012A139]
- Anhui Normal University
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This article reviews the progress made in the past 5 years in the field of direct and non-enzymatic electrochemical sensing of glucose. Following a brief discussion of the merits and limitations of enzymatic glucose sensors, we discuss the history of unraveling the mechanism of direct oxidation of glucose and theories of non-enzymatic electrocatalysis. We then review non-enzymatic glucose electrodes based on the use of the metals platinum, gold, nickel, copper, of alloys and bimetals, of carbon materials (including graphene and graphene-based composites), and of metal-metal oxides and layered double hydroxides. This review contains more than 200 refs.
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