Journal
MICROCHIMICA ACTA
Volume 176, Issue 1-2, Pages 1-22Publisher
SPRINGER WIEN
DOI: 10.1007/s00604-011-0678-0
Keywords
Liquid phase microextraction; Single drop liquid phase microextraction; Hollow fiber based liquid phase microextraction; Dispersive liquid phase microextraction; Ionic liquid
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Funding
- National Research Foundation (NRF) of Korea
- Ministry of Education, Science and Technology [2011-0010673]
- National Research Foundation of Korea [2011-0010673] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
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Liquid phase microextraction (LPME) is a popular technique for sample pretreatment before the trace determination of target compounds from complex matrices, examples being pesticides in environmental and food samples, or drug residuals in biological samples such as blood or urine. LPME is simple, affordable, easy to operate, and highly sensitive. It is a miniaturized implementation of conventional liquid-liquid extraction in which only a few microliters of solvents are used instead of several hundreds of milliliters. This review focuses on newly developed LPME-based techniques, their application to environmental and biological samples, on their limitations, and on future applications.
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