Forced flow paper chromatography: A simple tool for separations in short time

In the proposed simple, disposable forced flow paper chromatographic device the main features of the separation like the analysis of time, separation power were improved. The chromatographic paper strips embedded into a polydimethylsiloxane (PDMS) block can be considered as an adsorption column, on which the liquid can be pumped. In a single device numerous separations can be performed in multiplex mode. On-capillary spectrophotometric detection is capable to detect the separated zones with good sensitivity. (C) 2009 Elsevier B.V. All rights reserved.